1) Due to labor union salary rules about filming outside of Los Angeles County, the show is actually filmed at Raleigh Studios in Manhattan Beach (40 miles away from the actual Newport Beach) to reduce filming costs.

2) The Cohen's pool is only four feet deep, so the cast do the pool scenes on their knees.

3) Was originally intended to be called "Orange County", but a movie of the same name had recently come out.

4) 'Adam Brody' originally auditioned for the part of Ryan Atwood.

5) In an early draft of the series, Ryan Atwood was going to be Sandy Cohen's illegitimate child.

6) Seth's middle name is Ezekiel.

7) 'Adam Brody' (Seth Cohen) doesn't like boats, so when he sails away in episode 1.27 "The Ties That Bind" he is not in the boat at all. It is a 40-year old stunt double in a wig that is actually sailing the boat.

Chad Michael Murray was offered a role in the show, but he turned it down when he had the opportunity to play Lucas in "One Tree Hill".

9) Peter Gallagher and Mischa Barton were the first to actors to be signed to the show. The part that the producers had the most problems casting was Ryan, so the last actor to sign was Benjamin McKenzie who got cast in the last minute.

10) In the first couple of episodes, the Cohens have a maid and the Coopers have a dog. Somehow the maid and dog disappeared without a trace during the first season.

11) Melinda Clarke and Rachel Bilson were only meant to be guest stars, but their characters became so integral to the show's popularity that they finally got signed as regulars and appeared in the opening credits from season 2 and on.

12) When 'Adam Brody' tested for the role of Seth Cohen, he decided to improvise everything. That didn't sit well with writer Josh Schwartz who told the producers afterwords that he never wanted "to see that kid ever again". A month later, when they still had not found the right Seth, the producers called Brody back for another test. Despite Schwartz not liking the fact that Brody would not stick to the writing, he had to admit that there was something about him. Schwartz later confessed that Brody reminds him of himself in many ways - which in the end was perfect for the role of Seth, since it is based on he writer himself.

13) When Benjamin McKenzie was cast as Ryan, the producers were amazed that he looked so much like a young 'Russell Crowe (I)' . Later in the show, Ryan takes his girlfriend Marissa to the theaters, and upon leaving she says that she didn't enjoy the film because "'Russell Crowe (I)' never did it for me".

14) To go out with a bang in the third season, the producers spread the word that one of five different leading characters would die in the last episode of the season. Rumors spread that they had actually shot all five deaths to avoid exposure of the truth about which character was dying. Whether or not all five death scenes were shot or not was never confirmed.

15) Kelly Rowan is only 14 years older than Adam Brody, who plays her son.

IZZIE: "What's wrong with where he was living before?"
MEREDITH: "I don't know where he was living before."
IZZIE: "Probably a whorehouse."

ALEX: "Morning, Dr. Model."
IZZIE: "Dr. Evil Spawn."
ALEX: "Ooooh, nice tat. Do they airbrush that out for the catalogs?"
IZZIE: "I don't know. What do they do for the 666 on your skull?"

MEREDITH: "Okay, here it is, your choice... it's simple, her or me, and I'm sure she is really great. But Derek, I love you, in a really, really big pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes me hate you, love you. So pick me, choose me, love me."

ALEX: "So, Grey and Stevens really walk around in their underwear?"
GEORGE: "Um... Not all the time. I mean, some of the time. But not all the time."
ALEX: "Sexy underwear?"
GEORGE: "Yeah..."
ALEX: "And they just let you look at them?"
GEORGE: "Well, uh... yeah."
ALEX: "So they're like your sisters?"
GEORGE: "No! Not like sisters. Uh... no! I don't think of them like sisters."
ALEX: "But they're not coming on to you?"
GEORGE: "Well, not exactly."
ALEX: "And they don't expect you to do anything."
GEORGE: "No, but..."
ALEX: "Like sisters. Just like sisters."

CRISTINA: "We're in an elevator. That's your specialty, right? McDreamy moments in the elevator?"
DEREK: "Dr. Yang-"
CRISTINA: "You know what? For just a moment, I’m not Dr. Yang and you’re not Dr. Shepherd. You’re the guy who screwed up my friend. The guy who drove her to get a dog she can't keep, the dog she only got because her boyfriend lied to her about his wife."
DEREK: "I never lied to her."
CRISTINA: "Yes you are. You know, I know a liar when I see one because I am a liar."

GEORGE: "What happened today?"
IZZIE: "Nothing."
MEREDITH: "Nothing."
GEORGE: "Okay then."
IZZIE: "We don’t know everything about each other, George."
MEREDITH: "Yeah."
GEORGE: [pause] "True. Anybody wanna have sex?"

IZZIE: "I just... I just need some sex, George. You know, I just, I need sex NOW. You know what I mean?"
GEORGE: "No matter how hard you beg, I am not doing you."

MEREDITH: "I did a terrible thing."
DEREK: "We all do terrible things."
MEREDITH: "No... I... I really think that I have just lost all my friends."
DEREK: "You won't lose me."
MEREDITH: "You aren't my friend."
DEREK: "Sure I am."

MEREDITH: [to Derek] "Stop looking at me like that"
DEREK: "Like what?"
MEREDITH: "Like you've seen me naked."
DEREK: [smiles]

DEREK: "Meredith, I am so sorry. Addison. What are you doing here?"
ADDISON: "Well you'd know if you'd bothered to return any one of my phone calls."
MEREDITH: [confused]
ADDISON: "Hi, I'm Addison Shepherd."
MEREDITH: "Shepherd?"
ADDISON: "And you must be the woman who's been screwing my husband."
MEREDITH: [silence]

IZZIE: "We need to talk."
ALEX: "Why?"
IZZIE: "You kissed me."
ALEX: "Yes, I did."
IZZIE: "Should we... I mean, there's a discussion that we could have... if you wanted to have one?"
ALEX: "Look. Izzie. I kissed you, with tongue, and I plan to do it again and again. So get used to it. End of discussion.
IZZIE: [blushes] "Okay."

MEREDITH: "So that's it? Was that what I was to you? The girl you screwed to get over being screwed?"
DEREK: "You were like coming up for fresh air. It's like I was drowning and you saved me. That's all I know."
MEREDITH: [pauses] "That's not good enough."

MEREDITH: "Denial is not just a river in Egypt. It's a freakin' ocean."

ALEX: [sees George crouching down] "What are you doing?"
GEORGE: "Hiding. There's this VIP patient that likes me."
ALEX: "Well, that's good, right?"
GEORGE: "No, you don't understand. He likes me, likes me."
ALEX: "Hey, go for it, man. Get yours. I'm down with the rainbow."
GEORGE: [silence]
ALEX: [pauses] "Oh, are you not gay?"
GEORGE: "No."
ALEX: "Really? Dude, sorry."

MEREDITH: I... I slept with George. I slept w

Summer: The more time i spend with zach, the less times i think about ... God, what's his face? Built like a bean pole, curly hair, runs away like a little bitch on his sailboat, leaving nothing but a note for his girlfriend who cried over and over for him until the Fourth of July until she decides she doesn't cry over bitches on sailboats.
Marissa: Seth. his name. It's seth.
Summer: I know. I'm just doing this thing were I pretend I don't and I have to use a lot of descriptive insults to give voice to my inner pain.


Luke: Maybe I should just blow it off. Hit the beach. Let people get it out of their systems.
Ryan: No, it doesn't work like that. It's been three months and I'm still the kid from Chino who burned a house down.
Marissa: And I'm still the girl who tried to kill herself in Mexico.
Seth: Yeah ... and I'm still - I'm still - well, I'm still Seth Cohen.

Summer: I was being sarcastic.
Marissa: So was I.
Summer: Which we never were before Cohen showed up and introduced us to irony. Jackass.

Marissa: Are you limping?
Summer: Yeah, Cohen kneed me in the leg.
Marissa: Why?
Summer: Must have read it in Kama Sutra.
Marissa: So you guys had sex again?
Summer: If you can call it that. There were like limbs, everywhere.

Marissa: Last year's holidays were so much better.
Summer: Yeah, I got rejected by Cohen in a wonder woman costume and you got caught shoplifting.
Marissa: Well, at least it was memorable.

Marissa: "Hello, Mother. No I'm not coming home, okay, bye."
Julie: "Please ... Do not ... Uhh. She's such a little me."