By Raymond Cushing, AlterNet

http /www. alternet. org/story/9257/

The term medical marijuana took on dramatic new meaning in February, 2000 when researchers in Madrid announced they had destroyed incurable brain tumors in rats by injecting them with THC, the active ingredient in cannabis.

The Madrid study marks only the second time that THC has been administered to tumor-bearing animals; the first was a Virginia investigation 26 years ago. In both studies, the THC shrank or destroyed tumors in a majority of the test subjects.

Most Americans don't know anything about the Madrid discovery. Virtually no major U.S. newspapers carried the story, which ran only once on the AP and UPI news wires, on Feb. 29, 2000.

The ominous part is that this isn't the first time scientists have discovered that THC shrinks tumors. In 1974 researchers at the Medical College of Virginia, who had been funded by the National Institute of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice -- lung and breast cancer, and a virus-induced leukemia.

The DEA quickly shut down the Virginia study and all further cannabis/tumor research, according to Jack Herer, who reports on the events in his book, "The Emperor Wears No Clothes." In 1976 President Gerald Ford put an end to all public cannabis research and granted exclusive research rights to major pharmaceutical companies, who set out -- unsuccessfully -- to develop synthetic forms of THC that would deliver all the medical benefits without the "high."

The Madrid researchers reported in the March issue of "Nature Medicine" that they injected the brains of 45 rats with cancer cells, producing tumors whose presence they confirmed through magnetic resonance imaging (MRI). On the 12th day they injected 15 of the rats with THC and 15 with Win-55,212-2 a synthetic compound similar to THC. "All the rats left untreated uniformly died 12-18 days after glioma (brain cancer) cell inoculation ... Cannabinoid (THC)-treated rats survived significantly longer than control rats. THC administration was ineffective in three rats, which died by days 16-18. Nine of the THC-treated rats surpassed the time of death of untreated rats, and survived up to 19-35 days. Moreover, the tumor was completely eradicated in three of the treated rats." The rats treated with Win-55,212-2 showed similar results.

The Spanish researchers, led by Dr. Manuel Guzman of Complutense University, also irrigated healthy rats' brains with large doses of THC for seven days, to test for harmful biochemical or neurological effects. They found none.

"Careful MRI analysis of all those tumor-free rats showed no sign of damage related to necrosis, edema, infection or trauma ... We also examined other potential side effects of cannabinoid administration. In both tumor-free and tumor-bearing rats, cannabinoid administration induced no substantial change in behavioral parameters such as motor coordination or physical activity. Food and water intake as well as body weight gain were unaffected during and after cannabinoid delivery. Likewise, the general hematological profiles of cannabinoid-treated rats were normal. Thus, neither biochemical parameters nor markers of tissue damage changed substantially during the 7-day delivery period or for at least 2 months after cannabinoid treatment ended."

Guzman's investigation is the only time since the 1974 Virginia study that THC has been administered to live tumor-bearing animals. (The Spanish researchers cite a 1998 study in which cannabinoids inhibited breast cancer cell proliferation, but that was a "petri dish" experiment that didn't involve live subjects.)

In an email interview for this story, the Madrid researcher said he had heard of the Virginia study, but had never been able to locate literature on it. Hence, the Nature Medicine article characterizes the new study as the first on tumor-laden an

Researchers at the Medical College of Virginia discovered that cannabis is an incredibly successful herb for reducing many types of tumors, both benign and malignant (cancerous). The DEA and other federal agencies had ordered these tumor studies done after hearing erroneous reports of possible immunicological problems associated with cannabis smoke. But, in 1975, instead of health problems, an apparent medical breakthrough occurred and successful tumor reductions were recorded! Following this remarkably positive discovery by the Medical College of Virginia, orders were immediately handed down by the DE and the National Institute of Health to defund all further cannabis/tumor research and reporting! Millions of Americans who might be alive today are dead because of these and other DEA orders regarding marijuana. Since 1996, the Medical College of Virginia has again applied to receive grants for cannabis research and has been turned down by the DEA.

Since there is no scientifically demonstrable reason why cannabis is considered under Irish Law more harmful to individuals or society (notwithstanding the dangers associated due to it's current criminal standing) than alcohol, justification of the legislation requires acceptance in law of particular cultural and religious moral principles, which is expressly forbidden by a provision in article 44 or the Irish Constitution.

Specifically, the religious principle which is endowed favour is: "that alcohol is a morally acceptible narcotic, but that cannabis or marijuana is not."

From Article 44 of the Constitution :
"The state guarantees not to endow or favour any religion and not to discriminate on the grounds of religion."
'Religious Liberty' is liberty not just to practise your religion or lack thereof, but to be free from laws that are expressions of particular religious beliefs.
In light of this, I propose that Ireland's acceptance of the Single Convention on Narcotic Drugs should be conditional on the guarantee that the convention itself be grounded in acceptible standards of scientific enquiry, and not in cultural and religious moral principles which are not universally accepted.